Photos in UK media showed Harry walking off a plane early Tuesday on Vancouver Island, where the family spent time over Christmas.
The Duke of Sussex attended the UK-Africa Investment Summit in London on Monday, where he met with UK Prime Minister Boris Johnson, before flying across the Atlantic.
A royal spokesperson told CNN they would not comment on the family’s private schedule.
The prince’s departure from the UK follows a turbulent period in which Harry and Meghan agreed to give up their royal titles and end their official duties.
The couple made the shock announcement that they were stepping back from senior royal duties on Instagram on January 8, and the Queen announced a transition period had been agreed Saturday.
Under the terms of the deal, Harry and Meghan will no longer represent the Queen as working royals, splitting their time between the UK and North America as they work toward becoming financially independent.
On Sunday, Harry spoke about the developments at a charity event in London.
“The UK is my home and a place that I love,” Harry said in a speech. “That will never change.”
“The decision that I have made for my wife and I to step back is not one I made lightly,” he said.
“It was so many months of talks after so many years of challenges. And I know I haven’t always gotten it right, but as far as this goes, there really was no other option.”
“Our hope was to continue serving the Queen, the commonwealth, and my military associations, but without public funding,” he said. “Unfortunately, that wasn’t possible.”